Glucosamine and chondroitin are nutritional supplements that may relieve your joint pain. The possible beneficial effects of glucosamine and chondroitin, two popular supplements for patients with joint pain, have been making news in recent years.
Glucosamine and chondroitin are actually two different molecules found in healthy joint cartilage. The medical theory behind taking these supplements is that they would help the body repair cartilage that has been broken down by osteoarthritis (the most common "wear-and-tear" form of arthritis). Some popular glucosamine supplements are derived from shellfish; chondroitin supplements are often derived from shark or cattle. Both can also be made synthetically. The supplements are sold and packaged much in the same way vitamins are. Like vitamins, they are not subject to review or approval by the U.S. Food and Drug Administration.
Although the U.S. Food and Drug Administration has tentatively concluded that no studies to date have linked glucosamine and chondroitin to a reduced risk of developing osteoarthritis, a large study administered by the National Institutes of Health has shown that glucosamine and chondroitin, when taken together, significantly reduce pain in patients with moderate-to-severe osteoarthritis of the knee.1 In fact, the study showed that people taking the supplements experienced the same amount of pain relief as people who took non-steroidal anti-inflammatory medications (NSAIDs)2 – long the go-to medication for people with arthritis pain.
Look for a familiar, reputable brand name. If you have questions about the product, write to the manufacturer for more information. Ask your doctor about his or her experience with the supplement. And, most importantly, if you experience any adverse reactions, stop taking the supplement and call your doctor right away.
References
1. NCCAM: National Center for Complementary and Alternative Medicine. Backgrounder: Questions and Answers: NIH Glucosamine/Chondroitin Arthritis Intervention Trial (GAIT). National Institutes of Health. Available at: http://nccam.nih.gov/research/results/gait/qa.htm#a1. accessed Oct. 2008.
2. http://orthopedics.about.com/cs/supplements/a/glucosamine.htm, accessed Oct. 2008.